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December 2012 Archives

The Moon: Not Green Cheese After All

In 2011, the twin GRAIL space probes were launched to map what the moon is made of. Upon reaching the moon exactly one year ago, they began to carefully map the density of the entire crust of our largest satellite.

The mission was a complete success; the map was finished late this year. At that point, NASA put the probes into what's called a decaying orbit. The craft spiraled down towards the surface, falling lower each revolution until they crashed into the surface earlier this month to end the mission. The map they left behind (shown in the NASA image below) tells some interesting stories about the moon.

NASA Moon Map Sm.png

The Power of Asteroid Impacts

When you look at the map, craters pop out dramatically. The rings of color are the patterns left in the moon's crust by space rock impacts. Blue areas are less dense and red areas are more so. Since the moon doesn't have erosion (no wind, rain, rivers, living organisms to shape its surface), craters stay forever. An amazing 12% of the moon's surface is actually empty space, smashed in by impacts. This level of destruction is even greater than expected by astrophysicists.

The early solar system was a place where massive space rock impacts were frequent. The moon's surface is an indelible map showing the ultra-violent ferocity of this time.

The Moon Grows and Shrinks

Some features on the density map resemble giant slashes or lines. These are called dikes, and they indicate volcanic activity related to the growing and shrinking of the moon's crust. During its first billion years, the moon was very hot, and grew in size from volcanic activity. Eventually it cooled down, and now it is actually shrinking. These maps are the only known way to find and study this phenomenon.

The Moon is Made of Earth

No one knows for sure where the moon came from and how it ended up orbiting the earth. The most likely theory however, is that early in the planet's history, an enormous object (roughly the size of the moon) smashed into it. The resulting explosion was so violent that a moon's-worth of earth's rock was blasted into space. All that rock slowly coalesced into the moon.

The GRAIL data supports this theory, showing that both the earth and the moon contain about the same amount of aluminum. This would probably not be the case if the moon formed in some far away place and was "captured" by the earth's gravity.

December 2012 Archives

Uvula, Cerumen, & Coccyx: Your Body Is Weird

Your body is a temple, and what are temples usually filled with? Mystic, ancient texts that few people can read or understand. It's the same with your body's myriad muscles, bones and tissues. You've got a boatload of them, and many have strange names and even odder functions. Here are a few:

Uvula - The uvula is a short, rounded projection of pinkish connective tissue that hangs down in the back of your throat. Not sure what I'm talking about? Look in the mirror and say "Ahhhhhhh." You've now seen your uvula.

The stalactite-like tissue is used in the formation of certain guttural sounds. Massaging it with a finger will also trigger the gag reflex. This makes it a wonder why some people choose to get their uvula pierced.

Tonsils_diagram.jpgCerumen - Cerumen is a bodily substance primarily composed of layers of shed skin, long-chain fatty acids, cholesterol, and alcohols. It's often yellowish and wet (but it can be gray and flaky), waxy, and secreted in the ear canal, almost like earwax... Okay, the jig is up. Cerumen is earwax, just a cooler, more science-y term for the stuff.

On a side note, you really shouldn't clean it.

Sternocleidomastoid - Want to get inspired? Doing so will necessitate that you flex your neck's sternocleidomastoid muscle. And by inspiration, I don't mean getting filled with the urge to perform an activity; I mean the act of breathing air through your mouth and into your lungs.

The sternocleidomastoid is a paired muscle found on either side of your neck towards the anterior. You use it to rotate and flex the neck as well as extend your head. It's one of the more overt neck muscles and is unique to mammals. That's why, when designing movie aliens to seem attractive and familiar to viewers, special effects artists make sure to include it.

"Even C3PO has it, in the form of little pistons on his neck. Watch Star Trek: The good guys always have them, and the bad guys don't. It's a classic alien designer trick," biologist Stuart Sumida told Slate.

Sternocleidomastoideus.pngCoccyx: In one of the finest quotes that Wikipedia has to offer, the online encyclopedia reports that the coccyx, while the remnant of a vestigial tail, is "not entirely useless." Commonly known as the tailbone, it's a key attachment site for various muscles, tendons and ligaments, some of which are involved in the vital, custodial function of defecation. We also occasionally sit on our coccyx.

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December 2012 Archives

An Easy Way to Reduce Traffic Congestion?

The holidays are here, so everybody knows what that means: Last-minute gift-buying, restless children, and sitting in traffic while shuttling back-and-forth between your parents' house and your in-laws'. There isn't much we can do about the first two problems, but scientists are trying to figure out how to fix the last one.

In a new traffic study, researchers for the first time used cell phone data to track the locations of drivers in Boston and the San Francisco Bay Area. Typically, traffic studies rely on driver diaries, but the new method allowed for the collection of immense quantities of data, data which is far more accurate. By using cell phone data, they could pinpoint "major driver sources" (MDSs) and their relationship to traffic flow. 
shutterstock_94817578.jpg

What the researchers found surprised them. Most traffic congestion is due to just a handful of MDSs, which have a much higher than average commute time.

The authors modeled what would happen if traffic was reduced from 0.1% to 1%. They specifically focused on reducing traffic from the handful of MDSs with the greatest congestion. (In Boston, that was 15 MDSs; in the Bay Area, 12 MDSs.) The model predicted that targeting just these handful of sites would cause a major reduction in congestion and travel time.

It should be pointed out that in order to achieve such a reduction in congestion and travel time, the authors reduced traffic from the major MDSs anywhere from 2.5% to 25% in Boston and 2.7% to 27% in the Bay Area. That's a lot of cars to reduce. Most likely, tolling these high congestion MDSs would be the best way to get drivers out of their cars, but that's rarely a popular solution.

And which cities could benefit the most from this research? Here's a list of American cities with the worst traffic:

1. Honolulu
2. Los Angeles
3. San Francisco
4. New York City
5. Bridgeport, CT
6. Washington, DC
7. Seattle
8. Austin
9. Boston
10. Chicago

Perhaps city planners in these cities should take note of this study.

Source: Pu Wang, Timothy Hunter, Alexandre M. Bayen, Katja Schechtner & Marta C. González. "Understanding Road Usage Patterns in Urban Areas." Scientific Reports 2, Article number: 1001 doi:10.1038/srep01001

(Image: Traffic via Shutterstock
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December 2012 Archives

Have a Very Merry Christmas... Insect Infestation!

shutterstock_115252588.jpgHark! The holiday season is upon us!

All across the country, it's a time for sharing and caring, harmony and love; a time to lend help to those in need and appreciate your neighbors, family, friends, and fellow citizens.

For approximately forty million American households, the holiday season is also a time to bring a filthy, scratchy, allergy-inducing, insect-ridden tree into the living room, where it will remain for as long as a month.

The typical Christmas tree is teeming with holiday decor: needled branches adorned with trinkets and baubles, wreathed in sparkling lights. But behind the ornate festivity lurks a genuine infestation. Aphids, lice, weevils, spittlebugs, moths, mites, and even the odd spider may reside therein.

"There are a number of insects hiding in a Christmas tree," says Bjarte Jordal, an associate professor at the University of Bergen in Norway. "In research on Christmas trees there have been found as many as 25,000 individual creep in some of the trees."

"They go to sleep for the winter, or hibernate to use the technical term," Jordal adds. "They usually empty their bodies of fluids and produce a chilled liquid and are completely inactive. But they reawaken when the tree is brought into the heat of the living room."

Most of these insects are invisible to the human eye or are simply adept at hiding. They primarily linger on or in the tree for the duration of the season, but occasionally do attempt to branch out. In 2010, a Virginian reported an instance in which a surplus of giant conifer aphids descended from their conifer confines and overstayed their welcome:

...all of a sudden, one day I saw them all over the floor surrounding the tree. I kept finding more and more spreading out from around the tree into other rooms. Finally we saw they were all over the trunk and branches of the tree.
But fret not, stories like this are extremely rare, so don't let them spoil your holiday cheer! Besides, tree-infesting insects are, for the most part, completely benign. According to Jordal, "As they cannot feed on the limited plants found in most households, the bugs will quickly dry out and die. These insects and bugs do not constitute any risk or danger to people or furniture."

Cinara_piceae.jpgStill, nobody wants to awaken on Christmas morning to find their neatly-wrapped gifts littered with insect corpses. Thus, to lessen the potential for a holiday insect invasion, inspect any tree -- be it a conifer, pine, fir, or spruce -- thoroughly before purchasing. Search for buggy indications like whitish eggs, small holes with sawdust trails, and the creepy-crawlies, themselves. Before bringing the tree into the house, give it a good shake. This should evict many of the insect residents. 

Remember, says Jordal, "when you bring a tree into the comfort of your living room, the tree carries a part of nature with it." If such an earthy notion appeals to you, feel free to extend the holiday spirit to the thousands of insect interlopers. After all, the season is (theoretically) all about sharing and caring!

However, there's no shame in excluding our six- and eight-legged neighbors from those sentiments. Santa doesn't deliver lumps of coal for kicking bugs out of pine trees.

(Images: 1. Christmas Tree via Shutterstock 2. Conifer Aphid by Enlil2 via Wikimedia Commons)

December 2012 Archives

Are We Living in The Matrix?

Can we know if we are actually living in a computer simulated universe? New physics research gives us some possible clues about how we might tell and how hard it would be to artificially create the world we experience. This work is at the fine border between scientific speculation and speculative science. Keep in mind that it is about as far from practical and testable as physics can get.

The heart of the matter is to determine whether the space we live in has infinitely small distances. What do I mean by that? Everyday intuition tells you that you can take one step, or half a step, or half of a half of a step, or a half of a half of a half (1/8) of a step, and so forth. The universe, so far as we know, probably allows you take smaller and smaller steps forever (infinitely).

However, when a computer simulates reality, it does things differently. It can't use infinitely small space because it can only store a limited (finite) number of things in its memory. This places a limit on the very smallest step you can take. So, if we were living in a simulation, we might find out that trying to take too small of a step is impossible!

One of the very best current computer simulations of reality is lattice QCD. QCD is the quantum theory of the strong force. It describes what protons and neutrons are made of and how they interact to form atomic nuclei and carry out nuclear processes. Computer simulations of QCD must use space with a limit on how small the size of a step can be. These simulations assume that space has a smallest possible step to move (or set of positions that you can occupy). Currently, the smallest step is somewhere around one tenth to one twentieth of a femtometer (10-16 m = 10-1 fm). This is about one hundred times smaller than the nucleus of an atom (2-15 fm).

To simulate a cube of space the size of the period on this page, you would need roughly 1035 possible steps you can take or locations you can be at in that space. Right now our fastest computers could never do this in a trillion years.


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Lattice QCD simulation (Brookhaven National Laboratory)


This work analyzes extremely high energy bursts from outer space, called cosmic rays. Based on the energy of these rays, physicists claim that the space they come from must have steps at least as small as one millionth of one billionth of a femtometer (10-27 m = 10-12 fm). So if we are being simulated by some future computer, it must be incomprehensibly powerful to be able to analyze this many possible steps. (Think trillions of years to simulate the size of an atom.)

This raises a new question. Is it even possible to build such a computer and carry out a simulation this powerful? While we have been experiencing approximately 50 years of unbelievably high (and consistent) increase in computer power, it would take centuries (or millennia or more) of growth continuing at the same rate for this to be possible for us. Furthermore, there are certain other problems, like whether there are enough atoms in the universe to build such a powerful computer, which no one has any idea about.

While this new evidence gives us something to think about, we are still back to essentially the same ancient conundrum. Before the computer age, philosophers wondered if we could all be living in someone else's dream. Like that old puzzle, the new practical conclusion is that we still can't tell, and so we might as well not worry about it.


December 2012 Archives

How to Avoid Spontaneously Combusting

shutterstock_119917441.jpgIt's a nagging worry that constantly loiters in the recesses of the mind: "Will today be that day I spontaneously combust?"

I'm hard-pressed to think of a worse way to go. One day, you might be walking down the street, suffering from a faint tinge of indigestion, when suddenly, poof; you're up in flames. Or perhaps you might be slouched in an armchair, lightly dozing and watching football, when the temperature of the living room unexpectedly jumps a few hundred degrees. Nope, that's not the furnace malfunctioning; it's just your torso... on fire.

The only consolation of combustion is this: the unadulterated pain would rapidly trigger the body's vasovagal reflex, inducing welcome, numbing unconsciousness in a matter of seconds.

There are no credible eyewitness accounts of spontaneous combustion, but the aftermath is described like so: Remains are found in the form of an ash heap, but the legs remain relatively unscathed. Furthermore, the surroundings show minimal signs of fire damage. Only the deceased seems to have burned.

Fewer than 150 cases of spontaneous human combustion have been reported over the last two thousand years. The rareness has rightfully engendered skepticism as to whether the condition truly exists. After all, the human body is approximately sixty percent water. It's simply not flammable.

Yet the unexplained cases still beg an explanation.

"The main theory was always alcoholism," microbiologist Brian Ford told BBC Radio. "People always said that people would drink too much alcohol. Their tissues would become soaked in alcohol, and they'd become inflammable."

This false belief has persisted despite the work of noted German chemist J. von Leibig, who, in 1851, pointed out that anatomical specimens preserved in 70% ethanol don't catch fire. Leibig went even further to substantiate the point. In tests that probably wouldn't pass ethics reviews today, he injected rats with ethanol over prolonged periods and tried to set them on fire. It didn't work.

Seeking an answer to the combustion conundrum, Ford recently searched through the well-documented cases of spontaneous human combustion and realized one commonality: all of the victims seemed to have been unwell. When we're sick, or the body is severely stressed, blood glycogen -- a carbohydrate that our muscles use for fuel -- can become easily depleted. This leads to fat molecules getting broken down and used as energy, instead. If the process is accompanied by cellular starvation, which can occur during chronic illness or even during a strenuous gym workout, acetone can be produced.

It's acetone that Ford theorizes may be the culprit for spontaneous human combustion. Not only is it highly flammable, it can also easily mix with water and lipids, and can thus permeate throughout the body.

To test his theory, Ford constructed 1/12 scale replicas of humans using pig tissue previously soaked in acetone. When set alight, the test dummies blazed magnificently, leaving, as Ford described in NewScientist, "a pile of smoking cinders with protruding limbs," almost identical to the documented human cases of spontaneous combustion.

Ford openly acknowledges that his experiments are by no means conclusive, though they do present the most plausible explanation yet.

Don't fret; it's extremely unlikely (almost impossible) that a human will simply catch fire without an external catalyst of some sort. Our bodies aren't hazardous chemical factories on the brink of disaster. 

But just in case these musings don't assuage your fear of bursting into flames, can you take a couple simple steps to further mitigate the meager chances that you'll spontaneously combust:

1. Avoid activities and diets which promote ketosis, the bodily state where levels of ketones -- like acetone -- are elevated. These include alcoholism, starvation, and diets based on low-carbohydrate and high fat/protein intake.

2. Avoid potentially dangerous sources of flame or high temperature, especially when drowsy. And don't smoke.

(Image: Attempted Combustion via Shutterstock)

December 2012 Archives

A Universal Sense of Scale

"When I look up at the night sky and I know that, yes, we are part of this Universe, we are in this Universe, but perhaps more important than most of those facts is that the Universe is in us. When I reflect on that fact, I look up -- many people feel small, because they're small, the Universe is big -- but I feel big, because my atoms came from those stars. There's a level of connectivity -- that's really what you want in life. You want to feel connected, you want to feel relevant. You want to feel like you're a participant in the goings on and activities and events around you. That's precisely what we are, just by being alive."

-Neil deGrasse Tyson


Stop. Look around. What do you see? A computer perhaps? A chair? A pen? A cup of coffee?

We're surrounded by objects scaled to our existence: clothes that fit us (hopefully), cars to move us, buildings to shelter us.

Your immediate world, the one in which you exist each and every day, is -- in a way -- a deception, a cleverly constructed ruse that skews your sense of scale. There's nothing wrong with this. After all, why shouldn't we tailor our environment to be exactly proportionate to ourselves and our needs?

But there's a vast universe out there, filled with organisms and objects invisible to our direct perception, or too gargantuan for us to comprehend.

There are neutrinos: tiny, subatomic particles moving close to the speed of light. At any given time, about 30 million of these particles flit around inside you. If you sliced a pencil in half (length-wise) seventy-three times, you'd whittle down to about the size of a neutrino -- one yoctometer (0.000000000000000000000001 meters).

Much, much farther up the size ladder, we find the carbon atom, the basic unit of the element fundamental to all life on Earth (yes, including you). With an atomic radius of 70 picometers, it's positively gigantic compared to a tiny neutrino. Yet still, if I placed 50 septillion (10^24) carbon atoms onto the open palm of your outstretched hand, you'd only be holding a measly mass of one kilogram.

The carbon atom is dwarfed by one of the smallest carbon based lifeforms: a ciliate protist. These microscopic, single-celled organisms inhabit lakes, ponds, oceans, rivers, and soils. You can't see them with your naked eye, but you can view them clearly under a microscope, provided, of course, that you've magnified at least 100 times.



4.2 billion kilometers away from Earth, lies the dwarf planet Pluto. You might be surprised to find out that its diameter (about 2,300 kilometers) is a little more than half of the length of the United States (4,200 kilometers). No wonder why it lost its planet status!

Just outside our galactic neighborhood, 18,000 light years away, we find the comparatively small Stingray Nebula. I say comparatively because it's only one-tenth the size of other known planetary nebulae. But this astronomical infant is still 130 times the size of our solar system!

480px-Stingraynebula.jpgAlas, the blobby, green and red Stringray Nebula is but a blip compared to the Milky Way Galaxy. Grab a piece of printer paper and make a dot with a fine point pen anywhere on the sheet. The dot would approximately be the Stringray Nebula. The sheet would be the Milky Way.

Our wondrous universe contains objects and organisms great and small. It's difficult to precisely determine where we fit in on this grand scale. The average human is 7 x 20^18 times more massive than a small virus, and 2.43 x 10^29 times less massive than the largest known star, VY Canis Majoris. Depending upon how you want to picture yourself in the grand scheme of things, you can elect to be a giant or an invisible dot.

But no matter where you fit in within the Universe, the one thing for certain is that you do fit in.

(Image: Stingray Nebula via NASA, Matt Bobrowsky)

December 2012 Archives

Ebola Decoy Protein Fools Immune Response

English: Biosafety level 4 hazmat suit: resear...

Biosafety Level 4 (BSL-4) lab where Ebola research is conducted. (Photo: Wikipedia)

The Ebola virus simultaneously elicits fear and fascination. It causes a horrifying death for its victims, who suffer from a hemorrhagic fever. Even though Ebola is primarily transmitted via direct contact with infected organisms or their fluids, recent research suggests that Ebola may also be transmitted through the air. Creepy enough as all that is, new research demonstrates that Ebola may have yet another trick up its sleeve.

But first, a little background:

The surface of the Ebola virus is covered with glycoprotein (GP), which binds host cells, allowing the virus to enter. Ebola is an RNA-based virus, which means its genetic information is stored in RNA, not DNA. Thus, it has to use a special enzyme (an RNA-dependent RNA polymerase) to create mRNA (the molecule which is translated into protein). This error-prone enzyme is vital to generating GP, which comes in two forms. The first is a full-length version, which is generated by a mysterious process known as RNA editing. Essentially, the polymerase enzyme purposefully mis-transcribes the RNA genome, about 20% of the time, to generate an "edited" mRNA from which the full-length version of GP is translated. The other 80% of the time, editing does not occur, and a shorter GP is produced. This short GP is secreted outside of the virus-infected cell and is known as secretory GP (sGP). 

Now, researchers have demonstrated that sGP is a clever invention. The Ebola virus appears to subvert the host's immune response by using sGP as a decoy to divert away precious antibodies.

Full-length GP is prominently displayed on the surface of the virus, and a successful human antibody response needs to target this protein. But, Ebola doesn't want that to happen, as it would neutralize the virus and prevent it from infecting cells. To counter this immune assault, Ebola deploys sGP, which subverts the immune response in two ways.

The first way is by passively absorbing antibodies directed at the full-length GP. Full-length GP and sGP share many structural features, so antibodies directed against the full-length GP can be tricked into binding the decoy sGP.

But, there's a second, more insidious way that sGP can subvert the immune response. It can trigger the proliferation of B-cells (antibody-producing cells) that preferentially bind sGP. In other words, sGP redirects the immune response to produce antibodies more suitable for binding the decoy sGP, not the full-length GP. Because so much sGP is produced by Ebola, this decoy protein skews the immune response toward attacking it, leaving the full-length GP on its surface free of neutralizing antibodies and, hence, free to attack host cells. The authors refer to this new pathogenic mechanism as "antigenic subversion."

The researchers caution that such viral treachery may have implications for vaccine design.

Source: Mohan GS, Li W, Ye L, Compans RW, Yang C (2012). "Antigenic Subversion: A Novel Mechanism of Host Immune Evasion by Ebola Virus." PLoS Pathog 8(12): e1003065. doi:10.1371/journal.ppat.1003065.


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December 2012 Archives

Isaac Newton: World Will End in 2060, not 2012

While many Americans likely intend to skip town on Friday, December 21st and head out on a holiday vacation, they might inadvertently find themselves skipping the Earth altogether.

In case you haven't heard, a plethora of Doomsday scenarios are portended to play out on that date. (Soothsayers are covering all the bases, I suppose.) With such death and destruction imminent, why spend money on expensive plane tickets or resort accommodations? Even if you survive the Apocalypse, chances are that it will still spoil your holiday (what with the kids whining about fire, brimstone, and a lack of McDonald's). So don't risk disappointment! In Hitchhiker's Guide to the Galaxy fashion, you can lie down and put a paper bag over your head, instead!

Let's run down the predictions. If these aren't mutually exclusive, we'll certainly be in for a world of hurt:

  • The Earth may collide with Planet Nibiru.
  • Earth's magnetic polarity may suddenly reverse, crushing us all to smithereens.
  • A giant, unforeseen asteroid will strike the Earth.
  • There will be a planetary or galactic alignment that will somehow overload the Earth with, uh, gravity... cosmic rays... dark matter... and... um... sheer awesomeness? 

Should we take any of these scenarios seriously? At the risk of serious castigation from conspiracy theorists, I'm going to go out on a limb and say not, "No way," but, "No how."

V838_Mon_HST.jpg Though purported as planet Nibiru, this is actually the star V838 Monocerotis, and it won't collide with Earth.

There is no evidence that Nibiru exists, and if it did, astronomers would have been well aware of its destructive trajectory for over a decade. Geomagnetic shifts -- reversals in Earth's polarity -- actually do take place every 400,000 years or so, but they are quite harmless to planetary life and occur over thousands of years, not in one, supposedly bone-crunching moment. No asteroids are slated to pose a risk to Earth until 2020, and that asteroid -- 2012 TC4 -- has a 1 in 43,000 chance of impacting our planet. And astronomical alignments aren't remotely menacing, only tacitly fascinating to astronomers.

But while we may be in the clear this year, it's certainly not too early to be worrying about the next cataclysm that almost certainly won't happen! Calamitous portents abound over the coming decades, but I'd like to gloss over those fantastical predictions from zany whack jobs and focus solely on the forecast provided by one Sir Isaac Newton. After all, he was correct about gravity, the laws of motion, and the spectrum of white light -- heck -- why not about the end of the world?

GodfreyKneller-IsaacNewton-1689.jpgContrary to what you might think, Newton was not always the supreme rationalist that we've come to revere. He actually wrote more about theology and alchemy than science and math combined. Newton voraciously sought out patterns and hidden codes within the Bible and other holy texts, with the same dedication he lent to inventing calculus.

After much reading and surprisingly simple calculation, Newton arrived at a date for the end of the world as we know it: 2060. Luckily for us, he didn't mean "end" in a literal sense. He picked 2060 as the approximate date that Christ would return and establish a global kingdom of peace. Of course if Newton's prediction comes to pass, we might have to endure the great battle of Armageddon first, which probably won't be too pleasant.

(Images: 1. NASA and ESA   2. Sir Godfrey Kneller)
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December 2012 Archives

The Biggest Cash Prize in Science

What's the most lucrative prize a scientist can collect? The Nobel Prize has long been the premier award in all scientific fields. It nets each recipient a share of $1.2 million. The next most prestigious awards, such as the Israeli Wolf Foundation in physics and chemistry, pay around $100,000. This past year, styling himself after Alfred Nobel, Russian billionaire Yuri Milner decided to bestow prizes from his personal wealth. This is the Fundamental Physics Prize. Each winner's haul? Three million dollars.

Not only is this the largest monetary prize in physics (and all of science), but in some senses it carries the fewest strings attached. The first round of prizes were personally awarded by Milner. 3000 scientists do not vote by mail, unlike the Nobel selection process. 250 candidates are not discussed in secret; no reports are written and no committees meet. Future winners will be chosen by past winners and a very small board. Simple, quick, decisive, not bureaucratic.

The Fundamental Physics Prize has distinctive upsides. Being beholden to no large establishments, it is not caught up in politics or games. For example, Milner brushed off an idiotic New York Times question about the gender of recipients. (The overwhelming majority of physicists, and theoretical physicists, in particular, are male.) It can be awarded solely on merit and bypass politics.

The prize can change the life of a researcher in the heart of their career. A brilliant theorist waits, sometimes for decades, for experimental validation of their work before they can receive a Nobel. Peter Higgs is a perfect example. He published in 1964, and only now (thanks to the LHC), at age 83, is he eligible for the honor. 
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Milner's prize does have a glaringly unscientific facet however: it does not require experimental validation or realization of the honored work. Verification is essential to making sure that the prize honors scientific contribution. By choosing work that is speculative, the award can promote "creative output" more than strict scientific achievement. Additionally, this may promote ideological bias towards certain ideas regardless of their veracity. If string theory is some day rejected, several of the prize-winners may be seen as great thinkers who chased a red herring.

Taking money made from Farmville (Milner made millions from Zynga) and giving it to physics research is a great idea. Manny Pacquiao can make $23 million in a single night and not even be conscious at the end of it. Now a physicist can make $3 million for years of late nights working through math and physics textbooks and solving equations. It's about time.

(Image: Laser via Shutterstock)

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December 2012 Archives

Why America's Best Scientists Don't Get Funded

John Ioannidis doesn't mind stirring the pot. He is famous in the scientific community for very candidly explaining why scientists are getting many things wrong. He has gone so far as to claim that perhaps 90% of the studies in medical journals are incorrect, and he has the research to back it up.

A possible explanation for this is publication bias, the tendency of scientists to submit, and/or journals to accept, positive results (i.e., data which supports a particular hypothesis and is thus "exciting") instead of negative results (i.e., data which essentially says, "Nothing interesting happened here.") As a consequence, journals are crammed full of studies which are never replicated. Moreover, follow-up studies which fail to replicate previous ones often are not published.

Writing in The Atlantic, David Freedman summarizes the problem well:

Imagine, though, that five different research teams test an interesting theory that's making the rounds, and four of the groups correctly prove the idea false, while the one less cautious group incorrectly "proves" it true through some combination of error, fluke, and clever selection of data. Guess whose findings your doctor ends up reading about in the journal, and you end up hearing about on the evening news?
Other explanations include poor or biased experimental design, emphasizing statistical significance over biological relevance, or -- in extreme cases -- outright fraud.

As if all of that wasn't discouraging enough, Dr. Ioannidis has just struck again. This time, he has shown that America's best scientists aren't necessarily the ones to receive funding.

To arrive at this conclusion, he and his co-author Joshua Nicholson examined the most highly cited papers (1,000+ citations) written by U.S.-based biomedical scientists. A random sample of these papers showed that 60% of these exceptional scientists were not being funded currently by the National Institutes of Health (NIH) as principal investigators (i.e., "lead scientists"). shutterstock_52697125.jpg

Next, they examined professors in "study sections." These are groups of scientists who have been awarded NIH grants; because of their expertise, they are invited by the NIH to determine which of their colleagues also deserve NIH funding. As expected, most (83%) of study section scientists were currently receiving funds from the NIH.

But, here's the rub: How many of the study section scientists had written highly cited papers? A mere 0.8%. In other words, the scientists deciding which of their colleagues deserve funding are not themselves exceptional scientists. (They may be good scientists, but they aren't the best.) They also tend to award funding to research that is similar to their own.

Combined with the fact that a whopping 60% of exceptional scientists were not receiving NIH funding, Nicholson and Ioannidis lament that "not only do the most highly cited authors not get funded, but worse, those who influence the funding process are not among those who drive the scientific literature."

They believe that the current funding system has a built-in conflict of interest. Though the NIH is supposed to award funding based solely on merit, that clearly is not always happening. Why? Sometimes it is for benign reasons, such as scientists leaving academia or being in graduate school at the time of their high-impact publication.

But there is also a more malevolent reason, which the authors possibly hint at, but don't explicitly state: Study section scientists do not have a strong incentive to fund exceptional, creative colleagues. Why? Because, very likely, they are also competitors.

Nicholson and Ioannidis propose several solutions, one of which is essentially automatic funding for the truly exceptional scientists. Perhaps this could break the perception that the NIH is rewarding conformity over ingenuity.

Source: Joshua M. Nicholson & John P. A. Ioannidis. "Research grants: Conform and be funded." Nature 492, 34-36 (06 December 2012). doi:10.1038/492034a

Image: Pile of Money via Shutterstock
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December 2012 Archives

If asked out of the blue to picture a telescope, your mind might conjure up an image of a tall, rounded tower crowned with an immense dome, standing sentinel atop a mighty mountain under a clear, night sky teeming with twinkling stars.

The_VLT´s_Laser_Guide_Star.jpgIn all likelihood, you wouldn't envision a circular web of cables strung with 12,000 beach ball-like detectors, each cable about twice as tall as New York's Empire State Building, anchored two miles deep on the floor of the Mediterranean Sea.

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The telescopic array just described is called the Cubic Kilometer Neutrino Telescope, or KM3NeT for short. When operational, its primary mission will be to detect high energy, elusive, subatomic particles -- neutrinos -- and map their stellar sources.

Neutrinos move so fast, and are so tiny, that they can pass through almost anything. But traveling at near the speed of light, they occasionally strike atoms and leave tiny residual signatures of their presence, called Cherenkov radiation, which manifests as a cone of blue light. (That's why nuclear reactors glow blue.) By building KM3NeT at the bottom of the Mediterranean Sea, submersed in saltwater -- a medium much denser than air -- astrophysicists increase the chance that neutrino collisions will occur, and thus that the thousands of sensors affixed to the telescope will detect them.

As you've likely surmised, KM3NeT is undeniably different compared to land-based telescopes. Most fundamentally, while optical and radio telescopes train their gaze to the heavens above, KM3NeT actually focuses downward. It's arranged as such in order to avoid detecting particles with more local origins. Earth's atmosphere is already brimming with neutrinos, but KM3NeT isn't interested in those. Thus, the telescope uses the Earth as a sort of shield to filter them out.

At an estimated cost upwards of 250 million Euros, the project is a tad pricey. Luckily, seven European countries -- France, the Netherlands, Germany, Greece, Romania, Spain, and Italy -- are pitching in.

Construction has recently embarked on research structures in the Mediterranean, off the shores of Toulon, France; Porto Palo di Capo Passero, Italy; and Pylos, Greece. By Spring 2013, construction will be underway on the thousands of calibration and detection units required for the array. Full, on-site construction is slated to begin in 2014.

DOMBAR-DOMSupport.jpg Part of a detection unit with a detector attached.

When completed, KM3NeT will train its gaze toward the galactic center, where it will hopefully detect neutrinos from pulsars, the environs of black holes, and some of the universe's earliest supernovae. Astrophysicists hope that these long-distance cosmic messengers will reveal fascinating stories about cataclysmic events, and potentially even inform us on the nature of dark matter.

(Images: 1) VLT by G. Hüdepohl/ESO via Wikimedia Commons  2 & 3) KM3NeT via Marco Kraan/Propiety KM3NeT Consortium)

December 2012 Archives

The space probe Voyager 1 has flown through the asteroid belt, past Jupiter and Saturn, past Neptune and Uranus, beyond Pluto, and out to the very edge of the solar system. Along the way it has taken many famous pictures:


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Saturn and its Moons

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Neptune. Notice the giant blue spot, bigger than the Earth.

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Saturn

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Saturn's Moon Ariel

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Jupiter's atmosphere

The solar system is as huge as it is beautiful. But, it is tiny compared to the distance of the nearest star system. If the orbit of Pluto around the sun was the size of a dime, the diameter of the entire solar system would be a hockey puck with the sun at the center. Voyager has now reached the edge of that hockey puck. Alpha Centauri, the nearest solar system to ours, is like another hockey puck, one that is sitting almost three hockey fields (nearly two football fields) away.

Voyager's mission was not just to take pictures, but also to collect scientific data from the vast outer reaches of the solar system. This mission continues, as the probe still maintains continuous contact with the earth, from 11 billion miles away. 35 years in, most of the probe's instruments are still working, and only in the past few years have they begun to be intentionally shut down as the nuclear engine powering the craft slowly dies out. Some instruments will continue running all the way out to 2025, however.

Among these instruments are a magnetometer (which, as you might expect, measures magnetic fields), a cosmic ray detector, and a plasma wave measurement system (this essentially measures how many electrons are around). Astronomers use these instruments to learn about the area through which Voyager is now passing, the very furthest edge of the solar system. Astrophysicists have made theoretical predictions of what should be out there; now we get to find out firsthand.

Out beyond the planets, the main thing to see is the solar wind. This is a stream of charged particles (such as electrons) blasted out of the sun's atmosphere, into space and across the solar system. Howling past earth, it creates the auroras we see near the poles. The solar wind blows into the teeth of the interstellar wind, which is the general motion of charged particles throughout the space between stars. This has a different direction than the solar wind. The further from the sun Voyager travels, the weaker the sun's magnetic field and the solar wind should be. Soon, the spacecraft should reach a point where the two winds blow opposite each other to a standstill: the heliopause.

Voyager has begun to approach to this area over the past few years, and has been investigating it. Just this year however, things stopped going according to prediction. Instead of fading out, the solar magnetic field has leveled off and even grown stronger. It seems to merge with the interstellar field, in a way such that particles from the sun can be grabbed by the interstellar wind and whipped out far into space, and interstellar particles can find their way into the solar system.

As Voyager sails further, beyond the heliopause, the only thing we expect it to find out there is the cold lonely interstellar wind. After successful encounters with all four of the gas giant planets and now its work determining the composition of the outer solar system, this is already one of the most successful space missions of all time. Who knows though, further surprises may still be in store!
For almost half a century, many astronomers have been locked in the enduring Search for Extra Terrestrial Intelligence (SETI). Sizable telescopes -- astronomers' eyes and ears -- have been trained to the heavens, looking and listening intently for an otherworldly signal. To date, the search has proved fruitless. Apart from the background noise of space and the occasional astronomical event, SETI astronomers have heard naught but silence.

Except, that is, for a span of 72 seconds in the waning hours of August 15th, 1977, when the Big Ear Radio Observatory of Ohio State University detected a remarkable signal that still, to this day, remains unexplained.

That signal is known as the "Wow! Signal," named after the initial, astonished reaction of astronomer Jerry Ehman, who, upon sifting through the improbable data three days later, penned the following:

640px-Wow_signal.jpgTo the layperson, this picture may only seem to display an array of dull, random digits. But when you understand what it represents, you'll realize that it's anything but boring.

The numbers indicate the signal intensity detected by Big Ear for certain regions of space, defined as the ratio of signal strength versus the level of background noise. For example, a blank space would denote a signal between zero and one times as loud as the background noise of deep space, "1" would indicate between one and two times as loud, "2" between two and three times as loud, etc. Letters suggest a more intense signal. "A" denotes between ten and eleven times as loud, "B" between eleven and twelve times as loud, etc.

The Wow! signal -- the circled 6EQUJ5 -- meant that Big Ear detected a signal originating from the direction of the constellation Sagittarius that, at its strongest, was thirty times more powerful than the background noise of deep space!

But what's the big whoop? Scientists have discovered signals just as powerful from pulsars, quasars, supernovae and other natural astronomical phenomena. Why is Wow! special? As Robert Gray, author of the book The Elusive Wow: Searching for Extraterrestrial Intelligence, explained to The Atlantic:

With the "Wow!" there wasn't any noise on any of the channels except for one, and that's just not the way natural radio sources work. Natural radio sources diffuse static across all frequencies, rather than hitting at a single frequency... It was a very narrow band, very concentrated, exactly like a radio station, or a broadcast, from another world would look. 
Furthermore, the signal was detected at a frequency of 1420 Megahertz (1420.4556 MHz to be precise, according to Ehman). This is almost identical to the frequency at which hydrogen, the most common element in the universe, resonates. Years earlier, two Cornell physicists, Philip Morrison and Giuseppe Cocconi, writing in the journal Nature, postulated that aliens might attempt to make contact using that frequency, since it would likely be meaningful to a society with an understanding of science.

In the wake of the Wow! signal, with all signs improbably pointing to an extraordinary conclusion, Ehman took the data to colleagues John Kraus and Bob Dixon, and the trio set about the task of disproving the finding, as any good scientists would do.

Did the signal originate from a planet or an asteroid? Nope. It didn't fit the type of thermal emission expected from an astral body, and none were in the vicinity at the time of the transmission.

Did the signal come from a satellite or a spacecraft? No. Again, none were in the telescope's beam at the time of the Wow! source.

What about an airplane? Highly unlikely. No planes are allowed to transmit at 1420 MHz and the Wow! signal almost certainly originated from a fixed point with respect to the celestial background (the positions of stars), meaning that it came from light years away.

How about a computer glitch? Doubtful, as the systems were examined repeatedly afterwards. A ground-based transmission that bounced off space debris? An electromagnetic wave deflected from a star or galaxy? A wave sent from the twinkling of stars? All are plausible explanations, but deemed highly unlikely.

With rigorous analysis performed and all simple explanations pretty much ruled out, the only interpretation remaining was the most improbable one of all: a signal from an alien race. Yet since 1977, astronomers have focused their telescopes at the constellation Sagittarius, pricking up their ears in the direction where Wow! originated. They've heard nothing.

The ultimate rule of science is repeatability, and despite over one hundred follow-up studies on the Wow! signal, it's never once been observed again. "Thus, we have a small sample size of exactly one observation," writes H. Paul Shuch, emeritus executive director of SETI League. "This makes the signal intriguing, and enigmatic. It is suggestive of, but not proof of, our cosmic companions."

Years later, astronomical scientists like David Grinspoon still fantasize about the Wow! signal. Was it perhaps a snippet of conversation between two alien ships? And we were simply in the right place at the right time to eavesdrop?

But others, like Columbia University astronomer Caleb Scharf approach it with skepticism. It's very hard to exhaust the alternative possibilities when we are constantly learning more and more about the universe, he told NPR.

But, he added, "I can't in good conscience say that we will never see something. And I know that if we did, it would be amazing."

(Image: The Ohio State University Radio Observatory and the North American AstroPhysical Observatory (NAAPO) via Wikimedia Commons)

December 2012 Archives

Today, as evidenced by the undying popularity of Harry Potter, it seems incomprehensible that a large majority of Western society would ever look upon witchcraft with anything but sparkling adoration. Yet only four centuries ago, it probably was more common to burn witches than read about their marvelous adventures.

Europe of the 15th century was locked in the loosening, albeit terrible grips of the Black Plague. Death and decay besieged the landscape. Fear was rife, and the population was riven with it.

In trying times like these, humanity is best served by coming together. But more often than not, we unfortunately choose to tear ourselves asunder. Scapegoating becomes our primary goal. So it was in the 15th century, when the Pope and various countries labeled "heresy" as a corruption to be purged. Witches became the prime target.

In 1486, the Malleus Maleficarum -- "The Hammer of Witches" -- was written and published at the behest of Pope Innocent VIII. The manuscript called for witches to be hunted down and killed, and even contained instructions on how to recognize, torture, and execute them.

Matteson_Examination_of_a_Witch.jpgInquisitors sprung up throughout Europe, and, as Carl Sagan wrote in The Demon-Haunted World, the whole draconian enterprise quickly became an "expense account scam":

"All costs of investigation, trial, and execution were borne by the accused or her relatives --right down to the per diems for the private detectives hired to spy on her, wine for her guards, banquets for her judges, the travel expenses of a messenger sent to fetch a more experienced torturer from another city... Then there was a bonus to the members of the tribunal for each witch burned. The convicted witch's remaining property, if any, was divided between Church and State. As this legally and morally sanctioned mass murder and theft became institutionalized, as a vast bureaucracy arose to serve it, attention turned from poor hags and crones to the middle class and well-to-do of both sexes."

In Britain, witch-hunting was so lucrative that it actually fueled livelihoods. Witch-finders, also known as "prickers," received a sizable bounty for each girl or woman they turned over to the church. Because incentives were purely doled out per witch, prickers were often careless with their accusations. One man confessed that he had been the death of 220 women in his career.

In total, between 40,000 and 60,000 witches were executed in Europe between 1450 and 1750. The craze was fueled by inane fear and unquestioned belief, and it only ended when remedied with empirical reason, skepticism, and humanitarianism brought on by the Age of Enlightenment.