February 28, 2013

Circular RNA Adds to Geneticists' Confusion

Heidi Ledford, Nature News

AP Photo

Behold the latest curio in the cabinet of RNA oddities: naturally occurring circular RNA molecules that influence gene expression.

At least some of the loops, described in two papers published this week by Nature, act as molecular ‘sponges’, binding to and blocking tiny gene modulators called microRNAs. But the researchers suspect that the circular RNAs have many other functions.

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