January 21, 2011

Contagious Dog Cancer Steals Host Cell DNA

Imperial College London, Imperial College London


Imperial College London

A curious contagious cancer, found in dogs, wolves and coyotes, can repair its own genetic mutations by adopting genes from its host animal, according to a new study in the journal Science.

Scientists at Imperial College London have uncovered an unusual process that helps the cancer survive by stealing tiny DNA-containing 'powerhouses' (known as mitochondria) from the cells of the infected animal, to incorporate as its own. They say this may be because genes in the tumour's own mitochondria have a tendency to mutate and degenerate. The results are surprising because mitochondria and their genes are usually only passed from a mother to her offspring.

Read Full Article ››

TAGGED: mitochondria, mitochondrial DNA, cancer, dogs

RECOMMENDED ARTICLES

May 9, 2012
1 in 6 Cancers Worldwide Caused by Infection
Katie Moisse, ABC News
Roughly one in six cancers is caused by an infection, according to a global study highlighting the power of vaccines in cancer prevention.French researchers pooled data on 27 cancers from 184 countries to calculate the fraction... more ››
May 16, 2012
Hijacking Cell Motility to Combat Disease
Elise Lamar, HHMI Bulletin
Multicellular organisms harbor armies of cells on the move. Most are on goodwill missions—immune cells chase bacteria, and wound-healing fibroblasts rush in to fill gaps after injuries. Others, such as metastatic ... more ››
May 14, 2012
We Lose Control of Our DNA at Age 55
Sybille Hildebrandt, ScienceNordic
Our bodies are born to die, and the decay starts to kick in after we have turned 55. This is the point at which our DNA starts to degenerate, which increases the risk of developing cancer.This is the conclusion of a... more ››
May 10, 2012
Killing Cancer by Blocking Its Recycling System
Univ. of Pennsylvania
All cells have the ability to recycle unwanted or damaged proteins and reuse the building blocks as food. But cancer cells have ramped up the system, called autophagy, and rely on it to escape damage in the face of ... more ››
May 16, 2012
My Dog Listens, But Does He Understand?
Vanessa Dopker, PopSci
That depends. Dogs aren’t linguists, but they have remarkably good social cognition skills. Daniel Povinelli, a psychologist at the University of Louisiana at Lafayette, tested dogs’ ability to read cues from... more ››