 New Yorker On September 18, 2007, a few dozen neuroscientists, psychiatrists, and drug-company executives gathered in a hotel conference room in Brussels to hear some startling news. It had to do with a class of drugs known as atypical or second-generation antipsychotics, which came on the market in the early nineties. The drugs, sold under brand names such as Abilify, Seroquel, and Zyprexa, had been tested on schizophrenics in several large clinical trials, all of which had demonstrated a dramatic decrease in the subjects’ psychiatric symptoms. As a result, second-generation antipsychotics had become one of the fastest-growing and most profitable pharmaceutical classes. By 2001, Eli Lilly’s Zyprexa was generating more revenue than Prozac. It remains the company’s ... TAGGED: decline effect, statistical significance, publication bias, scientific research, scientific journals, scientific methodRECOMMENDED ARTICLES| All of us know the apocryphal tale where the mother-in-law “shares” a secret family recipe, but as much as you try, the cookies never taste the same as Mama’s. Of course, Mama’s withholding of the... more ›› |
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